Contact: Scott Jensen, (202) 249-6511  

WASHINGTON (May 6, 2014) - The National Academy of Sciences (NAS) released today a  report detailing their review of the U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS). This  congressionally-mandated report evaluated EPA's progress for improving the IRIS program by implementing the recommendations made by the National Research Council after their  review of the draft formaldehyde assessment in 2011.

The following statement can be attributed to the American Chemistry Council (ACC):

"We welcome this important report and are particularly encouraged that the NAS has recognized the need for EPA to address fundamental issues with the IRIS program. Importantly, the NAS report also singles out the valuable contributions made under the leadership of Dr. Ken Olden to address some of these concerns.

"The NAS report outlines several continuing concerns with the IRIS assessment methodology, including the lack of clear criteria for evaluating the available scientific information. Over the past several years, a strong case has been made detailing the critical need for improving IRIS in order to provide better support for public health decisions.

"The U.S. Government Accountability Office has listed IRIS as a 'high risk program,' and Congress has been compelled to act in a bipartisan fashion to call for this review by the NAS. This report marks yet another important milestone for identifying and addressing areas for improving the IRIS program. However, the release of this report should not be viewed as a stopping point. 

"ACC has strongly supported improvements in stakeholder engagement that Dr. Olden has implemented. Unfortunately, progress toward more substantive improvements, such as in data evaluation and evidence integration, has lagged. Today's report reiterates the need for continued improvement for EPA to achieve the scientific accuracy and transparency necessary for the development of high quality, reliable IRIS assessments.

"A number of NAS recommendations align well with  ACC's own principles for enhancing chemical assessments. For example, the NAS report calls on EPA to develop and implement consistent and transparent protocols for evaluating data for relevance, reliability and quality. It also advises EPA to improve study integration methods and recommends that the Agency move away from overreliance on single point estimates of toxicity values.

"We hope that EPA will take quick steps to adopt the recommendations of the report, including the development of a structured process to integrate the scientific evidence into assessments. Work on assessments currently in progress will benefit from a more transparent and systematic approach.

"ACC and our  members are committed to strengthening the process for conducting assessments under IRIS and other government assessment programs. We look forward to continuing our constructive work with EPA, including the adoption of many of the concepts outlined in our principles and this report."

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