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Dermal wipe sampling method development and validation for semivolatile and nonvolatile flame-retardant compounds TBBPA and TPP for use in occupational exposure assessments

Keywords: Absorption, dermal sampling, flame retardants, industrial hygiene, porcine skin, TSCA test orders

Authors: Gloekler L, Jappen O, Reynolds J, Thornton S, Sanders J, Maier A, Lynch H

Accurately estimating exposure is critical to assessing the potential health risks of chemicals. Characterizing dermal exposures to semivolatile or nonvolatile compounds in occupational studies can be challenging because of a lack of standardized procedures for dermal wipe sample collection and methods for sample analysis for most industrial chemicals, especially organic compounds. 

Flame Retardants
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Foundation for Chemistry Research & Initiatives

The Foundation for Chemistry Research and Initiatives (Foundation), is a 501(c)(3) tax-exempt organization established by the American Chemistry Council (ACC). Through partnerships with academia, research institutions, governmental and non-governmental organizations, and private corporations, the Foundation supports scientific research on various chemistries; the development of training programs for the safe use and application of products; and programs demonstrating chemistry’s contribution and benefits to society.

The Foundation was established in 1995 as the Research Foundation for Health and Environmental Effects (RFHEE).