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Guidance for Working with Aliphatic Diisocyanates 

The American Chemistry Council’s Aliphatic Diisocyanates Panel prepared this guidance to provide information about important health and safety considerations when working with aliphatic diisocyanates (ADIs). This paper provides additional information to what is contained in your supplier’s Safety Data Sheets (SDS), which are a main source of information for handling ADIs. Throughout this document, the term ADI refers to aliphatic diisocyanates, specifically hexamethylene diisocyanate (HDI), methylene dicyclohexyl diisocyanate or hydrogenated MDI (HMDI) and isophorone diisocyanate (IPDI), and their polyisocyanates. The term ADI polyisocyanates is used to address partially polymerized products from ADI monomers.

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American Chemistry Council

The American Chemistry Council’s mission is to advocate for the people, policy, and products of chemistry that make the United States the global leader in innovation and manufacturing. To achieve this, we: Champion science-based policy solutions across all levels of government; Drive continuous performance improvement to protect employees and communities through Responsible Care®; Foster the development of sustainability practices throughout ACC member companies; and Communicate authentically with communities about challenges and solutions for a safer, healthier and more sustainable way of life. Our vision is a world made better by chemistry, where people live happier, healthier, and more prosperous lives, safely and sustainably—for generations to come.