A study was initiated to evaluate the potential exposure of workers to inhalable and respirable particulates during the post-application trimming and cutting of open cell and closed cell sprayed polyurethane foam (SPF) insulation in interior applications. The primary purpose of the study was to establish sampling and analytical techniques which would be appropriate and practical for further field evaluations of worker exposure in actual SPF insulation applications. This study employed a protocol under controlled laboratory conditions designed to simulate an extreme case trimming situation.