This Q&A document discusses and illustrates the purpose and uses of EPA’s ToxCast™ data. It is intended to provide a technical summary of how to find, use, and interpret ToxCast data to facilitate ACC members’ understanding of advanced approaches for biological profiling of chemicals, and the use of this information within chemical safety assessments. It is not intended to be a comprehensive guide to ToxCast, rather an introduction and resource of where to find more information.