Exposure Science

Using data on the uncertainty of LOAELs to model the probability of observing adverse effects in low-dose studies of the toxicity of chemical mixtures

Keywords: dose addition, response addition, mixtures, LOAELs
Authors: Price P, Hagiwara S, Momoli F

Multidisciplinary perspectives on cumulative impact assessment for vulnerable communities: expert elicitation using a Delphi method

Collaborating Organization(s): ToxStrategies
Keywords: Environmental Justice, Cumulative Impact Assessment, Non-chemical stressors, risk modifiers
Authors: Verwiel A, Rish W

Principles and Elements for Creating and Sustaining Successful PPP for Environmental Community Monitoring Programs: Results from a Scoping Review and Interviews

Collaborating Organization(s): Johns Hopkins University Bloomberg School of Public Health, University of Maryland, Naiman Consulting, Texas Commission on Environmental Quality, Drexel University, Health Effects Institute, LaKind Associates LLC
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Principles and Elements for Creating and Sustaining Successful Public-Private Partnerships (PPPs) for Environmental Community Monitoring Programs: Results from a Scoping Review and Interviews with Stakeholders from Different Sectors

Collaborating Organization(s): LaKind Associates LLC, Johns Hopkins University Bloomberg School of Public Health, University of Maryland
Keywords: public–private partnership, environmental monitoring, community, trust, industry
Authors: LaKi...

Comprehensive Review of Frameworks, Methods, and Metrics for Cumulative Impact Assessment of Vulnerable Communities: A Science Perspective

 
Collaborating Organization(s): ToxStrategies
Keywords: chemical stressors, cumulative impact assessment, cumulative risk assessment, disproportionate health impact, environmental justice, non-chemical stressors, social determinants of heal...

Utilizing Threshold of Toxicological Concern (TTC) with High Throughput Exposure Predictions (HTE) as a Risk-Based Prioritization Approach for thousands of chemicals

 
Collaborating Organization(s): U.S. EPA Office of Research and Development, Procter & Gamble Company, Ted Simon LLC, American Chemistry Council
Keywords: TTC, high throughput exposure (HTE), risk-based prioritization
Authors: Patlewicz ...

Increasing confidence in new approach methodologies for inhalation risk assessment with multiple end point assays using 5-day repeated exposure to 1,3-dichloropropene

 
Collaborating Organization(s): ScitoVation
Keywords: 1; 3-Dichloropropene, Glutathione, IVIVE, inhalation toxicity, New Approach Methodologies (NAMs), PBPK, Repeated Exposure MucilAir
Abstract

Best practices for exposure model peer review – A SciPinion advisory panel report

Collaborating Organization(s): SciPinion, American Chemistry Council, Risksciences.net, Illahe Environmental
Keywords: exposure models, peer review
Abstract

Comparison of Rat Hepatocyte 2D-Monocultures and Hepatocytes Non-Parenchymal Cell Co-Cultures for Assessing Chemical Toxicity

 
Collaborating Organization(s): ScitoVation, 21st Century Tox Consulting LLC
Keywords: co-culture, hepatotoxicity, transcriptomics, risk assessment, New Approach Methodologies (NAMs), in vitro toxicity assessment
Abstract

Estimating Provisional Margins of Exposure for Data-Poor Chemicals Using High-Throughput Computational Methods

Collaborating Organization(s): U.S. EPA Office of Chemical Safety and Pollution Prevention, ScitoVation, U.S. National Toxicology Program, 21st Century Tox Consulting LLC, U.S. EPA National Center for Computational Toxicology
Keywords: TTC, com...