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Material Safe Handling Guidance

Erin Dickison

As with all chemicals, precautions are in place to help protect the persons handling methylene diphenyl diisocyanate (MDI) and toluene diisocyanate (TDI) during production, transportation, or processing of the chemical. The following offers resources developed to provide information on handling, storing and transporting MDI and TDI, including their use in making polyurethane foams. There are also helpful resources for the transportation of chemicals in general.

Materials Handling

CPI’s Documents

The Center for the Polyurethanes Industry (CPI) has developed a number of documents to assist with the safe handling and storage of TDI, MDI, and related polyurethane materials, including:

NIOSH Pocket Guide

The National Institute for Occupational Safety and Health (NIOSH) published a Pocket Guide to Chemical Hazards. The pocket guides for MDI and TDI available here: 4,4'-MDI Listing and 2,4-TDI Listing.


CPI has developed information about the safe transportation of TDI and MDI, including:

Other Transportation Resources:

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