Resource Library
Federal Government Resources
Guidance on health and safety, including use of appropriate protective equipment has been developed by federal agencies such as the Occupational Safety and Health Administration (OSHA) and the National Institute for Occupational Safety & Health (NIOSH).
- OSHA Informational Booklet: Personal Protective Equipment
- OSHA Respiratory Protection Advisor
- OSHA's Information on Diisocyanates
- NIOSH Respiratory Protection – Self Inspection Checklist
- NIOSH Online Pocket Guide to Chemical Hazards
- NIOSH Online Pocket Guide HDI Listing
- NIOSH Online Pocket Guide HMDI Listing
- NIOSH Online Pocket Guide IPDI Listing
- NIOSH Protective Clothing and Ensembles
- ASTDR Toxicological Profiles
Physical/Chemical Properties of HDI, IPDI and HMDI
- Working with Aliphatic Diisocyanates: This guidance document provides information about important health and safety considerations when working with aliphatic diisocyanates (ADIs).
Shown below is a physical properties chart for HDI, IPDI and HMDI

Additional Resources for Consumers
Aliphatic diisocyanates (ADI) are specialty intermediate chemicals used primarily to make durable coatings, adhesives, textiles, sealants and elastomers. ADIs are typically not sold directly for consumer use. Rather, they are sold primarily to industrial customers who use them as binders or hardeners during manufacturing processes. Volumes of ADI products used in North America are significantly smaller than the aromatic diisocyanates.1
Many of the products that we rely upon every day are safer, tougher and more reliable through the use of polyurethane products made with aliphatic diisocyanates chemistry. Extensive safety precautions are undertaken by the ADI and related industries to address the health and safety of users of ADI and to comply with all government regulations.
If you are interested in learning more about ADI chemistry and related products, here are some helpful resources you may want to visit:
Federal Government Agencies
A number of federal agencies provide useful information about many chemicals, including ADI.
- Agency for Toxic Substances and Disease Registry (ATSDR)
- Consumer Products Safety Commission (CPSC)
- Federal Trade Commission (FTC)
- Centers for Disease Control and Prevention (CDC)
- Environmental Protection Agency (EPA) Design for the Environment (DfE)
- National Institute for Occupational Safety and Health (NIOSH)
- Occupational Safety & Health Administration (OSHA)
- Pipeline and Hazardous Materials Safety Administration (PHMSA)
1 2018 End-Use Market Survey on the Polyurethanes Industry, Center for the Polyurethanes Industry, American Chemistry Council.